About the Product: Ursodeoxycholic acid is a secondary bile acid, produced in humans and most other species from metabolism by intestinal bacteria. Bile ducts can become blocked and cause cirrhosis in one or more parts of the liver. Ursodeoxycholic acid is a naturally occurring bile acid which is taken as either a tablet or liquid to try and prevent liver disease in people with cystic fibrosis.
Mechanism of Action— Ursodeoxycholic acid reduces elevated liver enzyme levels by facilitating bile flow through the liver and protecting liver cells. The main mechanism if anticholelithic. Although the exact process of ursodiol’s anticholelithic action is not completely understood, it is thought that the drug is concentrated in bile and decreases biliary cholesterol by suppressing hepatic synthesis and secretion of cholesterol and by inhibiting its intestinal absorption. The reduced cholesterol saturation permits the gradual solubilization of cholesterol from gallstones, resulting in their eventual dissolution.
Indication – For treatment of Primary billiory cirrhosis, dissolution of radiolucent gallstones and Hepatobiliary disorders associated with cystic fibrosis in children aged 6 to 18 years.
Storage Condition: Store in a cool place, protect from direct sunlight and moisture
Side Effects: nausea, diarrhoea, rashes and itching
Dosage— 300 mg OD FOR FATTY LIVER and can be given BD for very high sgot/sgpt level
For Gallstone 300 mg od dosage